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Ecstacy / "E" / MDMA


MDMA – colloquially known as ecstasy, often abbreviated as "E" or "X" – is an entactogenic drug of the phenethylamine andamphetamine class of drugs (Basically an "upper".
MDMA was first synthesized in 1912 by Merck chemist Anton Köllisch. At the time, Merck was interested in developing substances that stopped abnormal bleeding. Merck wanted to evade an existing patent, held by Bayer, for one such compound: hydrastinine. At the behest of his superiors Walther Beckh and Otto Wolfes, Köllisch developed a preparation of a hydrastinine analogue, methylhydrastinine. MDMA was an intermediate compound in the synthesis of methylhydrastinine, and Merck was not interested in its properties at the time. On 24 December 1912, Merck filed two patent applications that described the synthesis of MDMA and its subsequent conversion to methylhydrastinine.

Effects

The most common effects reported by users include:
A general and subjective alteration in consciousness
A strong sense of inner peace and self-acceptance
Diminished aggression, hostility, and jealousy
Diminished fear, anxiety, and insecurity
Extreme mood lift with accompanying euphoria
Feelings of empathy, compassion, and forgiveness toward others
Feelings of intimacy and even love for others
Improved self-confidence
The ability to discuss normally anxiety-provoking topics with marked ease
An intensification of all of the bodily senses (hearing, touch, smell, vision, taste)
Substantial enhancement of the appreciation for quality of music
Mild psychedelia, consisting of mental imagery and auditory and visual distortions
Stimulation, arousal, and hyperactivity (e.g., many users get an "uncontrollable urge to dance" while under the influence)
Increased energy and endurance
Increased alertness, awareness, and wakefulness
Increased desire, drive, and motivation
Analgesia or decreased pain sensitivity

After-effects

Effects reported by some users once the acute effects of MDMA have worn off include:
Psychological
Anxiety and paranoia
Depression
Irritability
Fatigue
Impaired attention, focus, and concentration,as well as drive and motivation (due to depleted serotonin levels)
Residual feelings of empathy, emotional sensitivity, and a sense of closeness to others (afterglow)
Physiological
Dizziness, lightheadedness, or vertigo
Loss of appetite
Gastrointestinal disturbances, such as diarrhea or constipation
Insomnia
Aches and pains, usually from excessive physical activity (e.g., dancing)
Exhaustion
Jaw soreness, from trismus or bruxism
When they occur, these after subacute effects are typically reported to last up to 3 to 7 days, with the exception of depression, which in some cases has become chronic.

Upon overdose (and this is could be just half a pill), the potentially serious serotonin syndrome, stimulant psychosis, and/or hypertensive crisis, among other dangerous adverse reactions, may come to prominence, symptoms of which may include:

Organ failure
Brain damage
Coma or death
Thought disorder or disorganized thinking
Cognitive and memory impairment potentially to the point of retrograde or anterograde amnesia
Acute delirium and/or insanity
Anxiety, paranoia, and/or panic attacks

Chronic use

Some studies indicate that repeated recreational users of MDMA have increased rates of depression and anxiety, even after quitting the drug.

Methods of Administration:

MDMA can be consumed orally in tablet or powder form. The powder can be dissolved into any liquid like a soda or energy drink. It is most often associated with energy drinks. 
Nasal insufflation (known colloquially as "snorting," "sniffing," or "blowing") is also a method of administrating MDMA but not as popular as taking it in tablet form.

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