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Herion / Thai

Heroin is a semi-synthetic opioid drug synthesized from morphine, a derivative of the opium poppy. As with other opioids, heroin is used as both an analgesic and a recreational drug. Heroin, is used as a recreational drug for the transcendent relaxation and intense euphoria it induces. Anthropologist Michael Agar once described heroin as "the perfect whatever drug." Tolerance quickly develops, and users need more of the drug to achieve the same effects. Its popularity with recreational drug users, compared to morphine, reportedly stems from its perceived different effects. In particular, users report an intense rush, a state of euphoria, that occurs while chemicals are being metabolized into (6-MAM) and morphine in the brain. Heroin produces more euphoria than other opioids upon injection.

Effects of Heroine

Like most opioids, medical grade Heroin doesn't cause many long-term complications other than dependence and constipation. Adulterated "street" Heroin however is considered to be one of the most harmful drugs especially if consumed intravenously.

Negative Effects 
This may lead to:
• The risk of contracting blood-borne pathogens such as HIV and hepatitis 
• The risk of contracting bacterial or fungal endocarditis and possibly venous sclerosis 
• Abscesses 
• Poisoning from contaminants added to "cut" or dilute heroin 
• Chronic constipation • Addiction with associated psychopathic behaviour 
• Increced Tolerance causing the addict to need more to achieve the same result 
• Physical dependence can result from prolonged use of all opioids, resulting in withdrawal symptoms on cessation of use 
• Decreased kidney function (although it is not currently known if this is because of adulterants or infectious diseases)

Cocaine is sometimes used in combination with heroin, and is referred to as a speedball when injected or moonrocks when smoked together. Cocaine acts as a stimulant, whereas heroin acts as a depressant. Co-administration provides an intense rush of euphoria with a high that combines both effects of the drugs, while excluding the negative effects, such as anxiety and sedation. The effects of cocaine wear off far more quickly than heroin, thus if an overdose of heroin was used to compensate for cocaine, the end result is fatal respiratory depression

The withdrawal syndrome from heroin (the so-called cold turkey) may begin within 6 to 24 hours of discontinuation of the drug; however, this time frame can fluctuate with the degree of tolerance as well as the amount of the last consumed dose. Symptoms may include: sweating, malaise, anxiety, depression, akathisia, priapism, extra sensitivity of the genitals in females, general feeling of heaviness, cramp-like pains in the limbs, excessive yawning or sneezing, tears, rhinorrhea, sleep difficulties (insomnia), cold sweats, chills, severe muscle and bone aches; nausea and vomiting, diarrhea, cramps, and fever.

Methods of Administration:

Oral (less Common),

Injection, Heroin powder is “cooked” on a spoon over a open flame to dilute. Users tend to initially inject in the easily accessible arm veins, but as these veins collapse over time, through damage caused by the acid, the user will often resort to injecting in other veins. The dose of heroin used for recreational purposes is dependant on the frequency and level of use, thus a first-time user may use between 5 and 20 mg, while an addict may require several hundred mg per day.

Smoking heroin refers to vaporizing it to inhale the resulting fumes, not burning it to inhale the resulting smoke. It is commonly smoked in glass pipes made fromglassblown Pyrex tubes and light bulbs. It can also be smoked off aluminium foil, which is heated underneath by a flame. This method is also known as "chasing the dragon"

Snorting Another popular route to intake heroin is insufflation (snorting), where a user crushes the heroin into a fine powder and then sharply inhales it (sometimes with a straw or a rolled up banknote, as with cocaine) into the nose where heroin is absorbed through the soft tissue in the mucous membrane of the sinus cavity and straight into the bloodstream.

Suppository, little research has been focused on the suppository (anal or vaginal insertion) method of administration, also known as "plugging". This method of administration is commonly administered using an oral syringe. Heroin can be dissolved and withdrawn into an oral syringe which may then be lubricated and inserted into the anus or vagina before the plunger is pushed.

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